Veterinary application (approved)
Animal reproductive management: Widely used for reproductive suppression or estrus cycle regulation in animals such as dogs, cats, and horses, such as suppressing estrus in female dogs and controlling sexual behavior in male horses.
Treatment of animal diseases: Used to treat diseases related to sex hormones, such as prostate disease and hyperadrenocorticism in dogs.
Human medical applications (some are in the research/development stage)
Reproductive endocrine disorders: It has been studied for the treatment of hormone-dependent diseases such as precocious puberty, endometriosis, and uterine fibroids.
Prostate cancer and breast cancer: As a GnRH agonist, it can theoretically be used as adjuvant therapy for hormone-sensitive tumors, but other analogues (such as leuprorelin and goserelin) are more commonly used.
Assisted reproductive technology: Pituitary downregulation in controlled ovarian stimulation (COS) cycles has been explored, but the current mainstream clinical drugs are other GnRH analogs.
Thin
